G37E (p.Gly37Glu) variant of TET2 (Methylcytosine dioxygenase TET2)
G37E (p.Gly37Glu) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
G37E (p.Gly37Glu) variant details
- p.Gly37Glu
- gnomAD 4-105234052-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.563
- REVEL 0.55
- MetaLR 0.31
- MetaSVM -0.44
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available