E10G (p.Glu10Gly) variant of TET2 (Methylcytosine dioxygenase TET2)
E10G (p.Glu10Gly) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
E10G (p.Glu10Gly) variant details
- p.Glu10Gly
- gnomAD 4-105233971-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.11
- MetaLR 0.10
- MetaSVM -0.96
- CADD 23.10
- PolyPhen-2 0.20
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available