A31T (p.Ala31Thr) variant of TET2 (Methylcytosine dioxygenase TET2)
A31T (p.Ala31Thr) in TET2 (Methylcytosine dioxygenase TET2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A31T (p.Ala31Thr) variant details
- p.Ala31Thr
- gnomAD rs1728672596
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.07
- MetaLR 0.19
- MetaSVM -0.82
- CADD 24.10
- PolyPhen-2 0.78
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available