W10R (p.Trp10Arg) variant of TECTA (Alpha-tectorin)
W10R (p.Trp10Arg) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
W10R (p.Trp10Arg) variant details
- p.Trp10Arg
- gnomAD rs1946357001
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.22
- MetaLR 0.08
- MetaSVM -0.94
- CADD 23.50
- PolyPhen-2 0.28
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available