W10C (p.Trp10Cys) variant of TECTA (Alpha-tectorin)
W10C (p.Trp10Cys) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
W10C (p.Trp10Cys) variant details
- p.Trp10Cys
- gnomAD 11-121102695-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.13
- CADD 24.20
- PolyPhen-2 0.44
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available