V60L (p.Val60Leu) variant of TECTA (Alpha-tectorin)
V60L (p.Val60Leu) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V60L (p.Val60Leu) variant details
- p.Val60Leu
- ESP rs376541939
- ExAC rs376541939
- gnomAD rs376541939
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.14
- MetaLR 0.24
- MetaSVM -0.93
- CADD 15.20
- PolyPhen-2 0.04
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available