P61S (p.Pro61Ser) variant of TECTA (Alpha-tectorin)
P61S (p.Pro61Ser) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P61S (p.Pro61Ser) variant details
- p.Pro61Ser
- TOPMed rs1041510767
- gnomAD rs1041510767
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.38
- MetaLR 0.43
- MetaSVM -0.43
- CADD 23.30
- PolyPhen-2 0.92
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available