L27I (p.Leu27Ile) variant of TECTA (Alpha-tectorin)
L27I (p.Leu27Ile) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L27I (p.Leu27Ile) variant details
- p.Leu27Ile
- TOPMed rs1041298366
- gnomAD rs1041298366
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -1.05
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available