L27F (p.Leu27Phe) variant of TECTA (Alpha-tectorin)
L27F (p.Leu27Phe) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L27F (p.Leu27Phe) variant details
- p.Leu27Phe
- TOPMed rs1041298366
- gnomAD rs1041298366
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.05
- MetaLR 0.06
- MetaSVM -0.98
- CADD 22.90
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available