I9F (p.Ile9Phe) variant of TECTA (Alpha-tectorin)
I9F (p.Ile9Phe) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
I9F (p.Ile9Phe) variant details
- p.Ile9Phe
- TOPMed rs1946356927
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.08
- MetaLR 0.08
- MetaSVM -0.99
- CADD 23.10
- PolyPhen-2 0.09
- SIFT 0.32
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available