G59D (p.Gly59Asp) variant of TECTA (Alpha-tectorin)
G59D (p.Gly59Asp) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
G59D (p.Gly59Asp) variant details
- p.Gly59Asp
- gnomAD 11-121105942-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.34
- CADD 23.50
- PolyPhen-2 0.37
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available