F57S (p.Phe57Ser) variant of TECTA (Alpha-tectorin)
F57S (p.Phe57Ser) in TECTA (Alpha-tectorin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
F57S (p.Phe57Ser) variant details
- p.Phe57Ser
- gnomAD rs1224604977
- Missense
- Variant Prioritization Score for Impact Estimate 0.76
- REVEL 0.81
- MetaLR 0.76
- MetaSVM 0.73
- CADD 28.50
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available