W99R (p.Trp99Arg) variant of TECRL (Q5HYJ1)
W99R (p.Trp99Arg) in TECRL (Q5HYJ1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
W99R (p.Trp99Arg) variant details
- p.Trp99Arg
- cosmic curated COSV10971
- TOPMed rs1189462482
- gnomAD rs1189462482
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- REVEL 0.28
- ESM-1b 1.00
- AlphaMissense 0.73
- CADD 27.30
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available