T84A (p.Thr84Ala) variant of TECRL (Q5HYJ1)
T84A (p.Thr84Ala) in TECRL (Q5HYJ1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
T84A (p.Thr84Ala) variant details
- p.Thr84Ala
- TOPMed rs939838974
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.32
- ESM-1b 1.00
- AlphaMissense 0.14
- CADD 25.50
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2e-06)
- Structural context available