P97S (p.Pro97Ser) variant of TECRL (Q5HYJ1)
P97S (p.Pro97Ser) in TECRL (Q5HYJ1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
P97S (p.Pro97Ser) variant details
- p.Pro97Ser
- rs757262911
- NCI-TCGA Cosmic COSV6708
- cosmic curated COSV67087
- ExAC rs757262911
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- REVEL 0.27
- ESM-1b 1.00
- AlphaMissense 0.14
- CADD 25.40
- PolyPhen-2 0.99
- SIFT 0.04
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available