I85L (p.Ile85Leu) variant of TECRL (Q5HYJ1)
I85L (p.Ile85Leu) in TECRL (Q5HYJ1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I85L (p.Ile85Leu) variant details
- p.Ile85Leu
- gnomAD rs1294718887
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.05
- ESM-1b 0.19
- AlphaMissense 0.11
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the South Asian population (allele frequency 1.7e-05)
- Structural context available