F65S (p.Phe65Ser) variant of TECRL (Q5HYJ1)
F65S (p.Phe65Ser) in TECRL (Q5HYJ1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
F65S (p.Phe65Ser) variant details
- p.Phe65Ser
- ExAC rs759596298
- TOPMed rs759596298
- gnomAD rs759596298
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.20
- CADD 23.80
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available