F2S (p.Phe2Ser) variant of TECRL (Q5HYJ1)
F2S (p.Phe2Ser) in TECRL (Q5HYJ1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
F2S (p.Phe2Ser) variant details
- p.Phe2Ser
- ExAC rs766911074
- TOPMed rs766911074
- gnomAD rs766911074
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.18
- CADD 23.60
- PolyPhen-2 0.35
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available