E11K (p.Glu11Lys) variant of TECRL (Q5HYJ1)
E11K (p.Glu11Lys) in TECRL (Q5HYJ1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
E11K (p.Glu11Lys) variant details
- p.Glu11Lys
- rs1055028800
- NCI-TCGA Cosmic COSV6708
- cosmic curated COSV67087
- gnomAD rs1055028800
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.08
- CADD 22.90
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available