D28G (p.Asp28Gly) variant of TECRL (Q5HYJ1)
D28G (p.Asp28Gly) in TECRL (Q5HYJ1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
D28G (p.Asp28Gly) variant details
- p.Asp28Gly
- NCI-TCGA Cosmic COSV6708
- cosmic curated COSV67085
- Ensembl rs1724942510
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.07
- CADD 22.70
- PolyPhen-2 0.01
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available