Q73H (p.Gln73His) variant of TBP (TATA-box-binding protein)
Q73H (p.Gln73His) in TBP (TATA-box-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
Q73H (p.Gln73His) variant details
- p.Gln73His
- ExAC rs764035011
- gnomAD rs764035011
- Missense
- Variant Prioritization Score for Impact Estimate 0.0822
- REVEL 0.05
- CADD 8.96
- PolyPhen-2 0.22
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available