P33T (p.Pro33Thr) variant of TBP (TATA-box-binding protein)
P33T (p.Pro33Thr) in TBP (TATA-box-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
P33T (p.Pro33Thr) variant details
- p.Pro33Thr
- gnomAD 6-170561833-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.30
- CADD 24.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available