M31I (p.Met31Ile) variant of TBP (TATA-box-binding protein)
M31I (p.Met31Ile) in TBP (TATA-box-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
M31I (p.Met31Ile) variant details
- p.Met31Ile
- 1000Genomes rs577070091
- ExAC rs577070091
- TOPMed rs577070091
- gnomAD rs577070091
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.17
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available