I27V (p.Ile27Val) variant of TBP (TATA-box-binding protein)
I27V (p.Ile27Val) in TBP (TATA-box-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data.
I27V (p.Ile27Val) variant details
- p.Ile27Val
- ESP rs150312586
- ExAC rs150312586
- TOPMed rs150312586
- gnomAD rs150312586
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.08
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the 1KG:MXL population (allele frequency 0.0081)