G24R (p.Gly24Arg) variant of TBP (TATA-box-binding protein)
G24R (p.Gly24Arg) in TBP (TATA-box-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G24R (p.Gly24Arg) variant details
- p.Gly24Arg
- cosmic curated COSV10507
- TOPMed rs970666552
- gnomAD rs970666552
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.10
- CADD 22.80
- PolyPhen-2 0.12
- SIFT 0.29
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available