A15T (p.Ala15Thr) variant of TBP (TATA-box-binding protein)
A15T (p.Ala15Thr) in TBP (TATA-box-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A15T (p.Ala15Thr) variant details
- p.Ala15Thr
- cosmic curated COSV10002
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.25
- CADD 22.20
- PolyPhen-2 0.05
- SIFT 0.11
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available