T78A (p.Thr78Ala) variant of TBK1 (Q9UHD2)
T78A (p.Thr78Ala) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T78A (p.Thr78Ala) variant details
- p.Thr78Ala
- TOPMed rs2040580437
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.06
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available