T77A (p.Thr77Ala) variant of TBK1 (Q9UHD2)
T77A (p.Thr77Ala) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
T77A (p.Thr77Ala) variant details
- p.Thr77Ala
- gnomAD 12-64464334-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.06
- CADD 15.90
- PolyPhen-2 0.02
- SIFT 0.54
- Population evidence available
- Structural context available
- Literature evidence available