S5T (p.Ser5Thr) variant of TBK1 (Q9UHD2)
S5T (p.Ser5Thr) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
S5T (p.Ser5Thr) variant details
- p.Ser5Thr
- ExAC rs756545042
- gnomAD rs756545042
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.02
- CADD 13.50
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available