N66S (p.Asn66Ser) variant of TBK1 (Q9UHD2)
N66S (p.Asn66Ser) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
N66S (p.Asn66Ser) variant details
- p.Asn66Ser
- gnomAD rs1164174065
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.56
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available