N42K (p.Asn42Lys) variant of TBK1 (Q9UHD2)
N42K (p.Asn42Lys) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
N42K (p.Asn42Lys) variant details
- p.Asn42Lys
- gnomAD 12-64460227-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.06
- CADD 14.10
- PolyPhen-2 0.11
- SIFT 0.38
- Population evidence available
- Structural context available
- Literature evidence available