L11V (p.Leu11Val) variant of TBK1 (Q9UHD2)
L11V (p.Leu11Val) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L11V (p.Leu11Val) variant details
- p.Leu11Val
- gnomAD 12-64455901-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.04
- CADD 14.20
- PolyPhen-2 0.11
- SIFT 0.48
- Population evidence available
- Structural context available
- Literature evidence available