L10P (p.Leu10Pro) variant of TBK1 (Q9UHD2)
L10P (p.Leu10Pro) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L10P (p.Leu10Pro) variant details
- p.Leu10Pro
- gnomAD 12-64455899-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.16
- CADD 24.30
- PolyPhen-2 0.93
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available