K60E (p.Lys60Glu) variant of TBK1 (Q9UHD2)
K60E (p.Lys60Glu) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
K60E (p.Lys60Glu) variant details
- p.Lys60Glu
- TOPMed rs978933862
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.34
- CADD 24.20
- PolyPhen-2 0.36
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.6e-06)
- Structural context available