I67T (p.Ile67Thr) variant of TBK1 (Q9UHD2)
I67T (p.Ile67Thr) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
I67T (p.Ile67Thr) variant details
- p.Ile67Thr
- gnomAD rs1460417033
- Missense
- Variant Prioritization Score for Impact Estimate 0.733
- REVEL 0.80
- CADD 26.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00028)
- Structural context available