G32D (p.Gly32Asp) variant of TBK1 (Q9UHD2)
G32D (p.Gly32Asp) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
G32D (p.Gly32Asp) variant details
- p.Gly32Asp
- gnomAD 12-64460196-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- REVEL 0.60
- CADD 27.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.8e-05)
- Structural context available
- Literature evidence available