G32C (p.Gly32Cys) variant of TBK1 (Q9UHD2)
G32C (p.Gly32Cys) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
G32C (p.Gly32Cys) variant details
- p.Gly32Cys
- gnomAD 12-64460195-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.59
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available
- Literature evidence available