F45F (p.Phe45Phe) variant of TBK1 (Q9UHD2)
F45F (p.Phe45Phe) in TBK1 (Q9UHD2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
F45F (p.Phe45Phe) variant details
- p.Phe45Phe
- rs11538420
- gnomAD 12-64460236-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.367
- CADD 14.60
- Most common in the HGDP:BASQUE population (allele frequency 0.023)
- Structural context available
- Literature evidence available