F35Y (p.Phe35Tyr) variant of TBK1 (Q9UHD2)
F35Y (p.Phe35Tyr) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
F35Y (p.Phe35Tyr) variant details
- p.Phe35Tyr
- gnomAD 12-64460205-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.18
- CADD 20.50
- PolyPhen-2 0.00
- SIFT 0.25
- Population evidence available
- Structural context available
- Literature evidence available