F35S (p.Phe35Ser) variant of TBK1 (Q9UHD2)
F35S (p.Phe35Ser) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
F35S (p.Phe35Ser) variant details
- p.Phe35Ser
- gnomAD 12-64460205-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.35
- CADD 23.50
- PolyPhen-2 0.10
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available