F35L (p.Phe35Leu) variant of TBK1 (Q9UHD2)
F35L (p.Phe35Leu) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
F35L (p.Phe35Leu) variant details
- p.Phe35Leu
- gnomAD 12-64460204-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.21
- CADD 24.10
- PolyPhen-2 0.02
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available