E74Q (p.Glu74Gln) variant of TBK1 (Q9UHD2)
E74Q (p.Glu74Gln) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
E74Q (p.Glu74Gln) variant details
- p.Glu74Gln
- ExAC rs751215465
- gnomAD rs751215465
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.31
- CADD 27.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available