E74E (p.Glu74Glu) variant of TBK1 (Q9UHD2)
E74E (p.Glu74Glu) in TBK1 (Q9UHD2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
E74E (p.Glu74Glu) variant details
- p.Glu74Glu
- rs759276622
- gnomAD 12-64460323-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.264
- CADD 10.70
- Most common in the East Asian population (allele frequency 0.00058)
- Structural context available
- Literature evidence available