D33Y (p.Asp33Tyr) variant of TBK1 (Q9UHD2)
D33Y (p.Asp33Tyr) in TBK1 (Q9UHD2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
D33Y (p.Asp33Tyr) variant details
- p.Asp33Tyr
- gnomAD 12-64460198-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.703
- REVEL 0.60
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available