D10G (p.Asp10Gly) variant of TARDBP (TAR DNA-binding protein 43)
D10G (p.Asp10Gly) in TARDBP (TAR DNA-binding protein 43) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D10G (p.Asp10Gly) variant details
- p.Asp10Gly
- gnomAD 1-11013756-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.41
- MetaLR 0.57
- MetaSVM -0.03
- CADD 32.00
- PolyPhen-2 0.02
- SIFT 0.04
- Population evidence available
- Structural context available
- TARDBP TAR DNA-binding protein 43, N-terminal domain domainome 1.0: score -0.208
- Literature evidence available