S37Y (p.Ser37Tyr) variant of SYNGAP1 (Q96PV0)
S37Y (p.Ser37Tyr) in SYNGAP1 (Q96PV0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
S37Y (p.Ser37Tyr) variant details
- p.Ser37Tyr
- gnomAD rs1475140370
- Missense
- Variant Prioritization Score for Impact Estimate 0.771
- CADD 24.50
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available