F21I (p.Phe21Ile) variant of SYNGAP1 (Q96PV0)
F21I (p.Phe21Ile) in SYNGAP1 (Q96PV0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
F21I (p.Phe21Ile) variant details
- p.Phe21Ile
- gnomAD 6-33420325-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- CADD 21.00
- PolyPhen-2 0.31
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available