S9C (p.Ser9Cys) variant of SYK (Tyrosine-protein kinase SYK)
S9C (p.Ser9Cys) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
S9C (p.Ser9Cys) variant details
- p.Ser9Cys
- gnomAD 9-90843923-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.20
- CADD 16.90
- PolyPhen-2 0.28
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available