S4G (p.Ser4Gly) variant of SYK (Tyrosine-protein kinase SYK)
S4G (p.Ser4Gly) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S4G (p.Ser4Gly) variant details
- p.Ser4Gly
- gnomAD 9-90843908-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.15
- CADD 10.60
- PolyPhen-2 0.00
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available