S3R (p.Ser3Arg) variant of SYK (Tyrosine-protein kinase SYK)
S3R (p.Ser3Arg) in SYK (Tyrosine-protein kinase SYK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S3R (p.Ser3Arg) variant details
- p.Ser3Arg
- TOPMed rs1233984148
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.29
- CADD 8.70
- PolyPhen-2 0.03
- SIFT 0.08
- Population evidence available
- Structural context available